Man Free of HIV After Stem Cell Transplant

An American man living in Germany appears to have been free of both leukemia and the virus that causes AIDS since he had a stem cell transplant for his leukemia three years ago.

German researchers report in the medical journal Blood that the transplant patient now shows no sign of having leukemia or HIV, suggesting that the transplant cured him.

But scientists warn that the case does not have practical implications for the treatment of millions of HIV patients worldwide.

Doctors say that the stem cell donor had a rare gene mutation that protects him from being infected with the AIDS virus.

The patient, Timothy Ray Brown, had his own immune system weakened by high doses of chemo-therapy and had stopped anti-viral therapy to treat AIDS.

In 2007 a doctor in Berlin performed a bone marrow transplant on him, using stem cells from the HIV resistant donor.

The intervention is very risky and potentially deadly. But doctors say that after three years, the so-called “Berlin patient” shows no trace of either HIV or leukemia.

HIV researches say even though the procedure is too dangerous and therefore not widely applicable, it gives hope that a cure for HIV infections can be found.

Tags: Germany, HIV, US

Posted in "Europe"

干细胞移植消除了男子的艾滋病毒

杭州蓝翔生物科技有限公司, 干细胞研究所 郭品正 翻译

生活在德国的美国男子似乎已经同时治愈了白血病和艾滋病病毒，他三年前为治疗白血病做了干细胞移植。

德国研究人员在医学杂志血液学上报告说，移植病人现在没有显示出有白血病或艾滋病毒的迹象，这表明已经通过（干细胞）移植治愈了。

但科学家警告说，此案不具备为全世界数百万患者的艾滋病毒治疗的实际意义。

医生说，干细胞捐献者有一种罕见的基因突变，突变能保护被感染艾滋病病毒。

病人，蒂莫西瑞布朗（Timothy Ray Brown），自身的免疫系统因大剂量的化疗而遭到削弱，已经停止了抗病毒疗法来治疗艾滋病。

2007年在柏林的医生对他进行了骨髓移植手术，使用的干细胞来自于对艾滋病毒有抵抗力的供体。

干预是非常危险和潜在致命的。但医生说，三年后，所谓的“柏林病人“没有显示出任何艾滋病毒或白血病的痕迹。

艾滋病毒的研究说，即使该程序是太危险了，不能得到广泛的应用；但它给了希望—治愈艾滋病毒感染方法可以找到。
标签：德国，艾滋病病毒，美国

张贴在欧洲

标签：德国，艾滋病病毒，美国

张贴在“欧洲”